Over the last half century, a quiet revolution has taken place. In
a series of breathtaking discoveries, biochemist Thomas Cech and a
diverse cast of brilliant scientists have revealed RNA at the
centre of biology’s greatest mysteries, from how life began to what
makes us human to why we age. At last, The Catalyst pulls back the
curtain to show how RNA—long sidelined as the passive servant of
DNA—defines life from its very origins to our future in the
twenty-first century.Recounting his own paradigm-shifting discovery
that RNA can catalyse biochemical reactions, as well as his work on
the “fountain of youth” telomerase, Cech unfolds how RNA holds the
key to the intricate machinery of our cells, the critical processes
of ageing and disease and the spectacular powers of breakthrough
therapies from CRISPR to mRNA vaccines. From one of our foremost
scientists, The Catalyst is a must-read guide to the present and
future of biology and medicine.
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